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KMID : 0378019890320110110
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New Medical Journal
1989 Volume.32 No. 11 p.110 ~ p.116
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Clinical Studies on MT-141(Cefminox, Meicelin) in the Treatment of Respiratory Tract Infections
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박원/Park, Won
이홍순/이학중/Lee, Hong Soon/Lee, Hak Choong
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Abstract
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The clinical investigation on a new cephamycin, MT-141, for the treatment of respirat. y tract infections such as pneumonia, acute mucopurulent bronchitis and acutely exacerbat-a chronic bronchitis was done.
Total number of patients who received MT-141 was 33 and 3 patients were excluded fro the evaluation of MT-141 effectiveness because two patients were proved to have pulmona y tuberculosis and one patient received MT-141 less than 3 days.
In remaining 30 patients, 18 of them were diagnosed as pneumonia and 12 patients bronchitis. Overall clinical, effectiveness in 30 patients was 76.7%(23 patients).
It was effective in 12 pneumonia patients(66.7%) and 11 patients(91.7%) of bronchiti., respectively.
Out of 33 patients, 4 patients showed elevated serum liver enzyme level during or just after MT-141 treatment and one patient showed thrombocytopenia, but they did not showed any subjective symptoms.
The abnormal laboratory findings were improved soon after the MT-141 discontinuation.
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